Peptide-Information

General Information

SPKB ID SPKB00152

Signal sequence MKPLILSAILITLCITSIAVSAPVEGIFADLHDSSHPYITDDVGVRMSAIKEENPDRHFVGDEIPDEAVIQSFKSKRREILFLLDDIGSAVEFIGSNLAQIEANHLSERVQFNWTHIRKNQPFGKREAEA

Length 130

Organism Komagataella pastoris?

UniProt ID NA,

Motif 1..130

Activity Information

Pathway SRP-dependent

Natural/Artificial Artificial

Subcellular location ER

Secretion efficiency Increase green fluorescent protein by 25 to 35 times

Type Sec/SPI

Structure Information

PDB ID NA,

Predicted Structure ID SPKB00152.cif

Structure SPKB00152.cif

Very high (pLDDT > 90)

Confident (90 > pLDDT > 70)

Low (70 > pLDDT > 50)

Very low (pLDDT < 50)

Loading PAE…

Expected Position Error (Ångströms)

Physicochemical Information

Molecular weight 14541.54174

Aliphatic index 101.3076923

Isoelectric point 4.950668512

Charge (pH=7) -6.588544051

Topological polar surface area 5970.58

Aromaticity 0.069230769

Average rotatable bonds 3.738461538

Number of hydrogen bond donors 204

Number of hydrogen bond acceptors 197

X logP energy -54.70181

Hydropathy

Literature Information

Title Optimized Komagataella pastoris yeast alpha-factor signal peptide and application

DOI NA,

Publication Year 2019

PubMed ID NA,