SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00150

Signal sequence   MRQVWFSWIVGLFLCFFNVSSA

Length  22

Organism  Artificial

UniProt ID  NA,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  Methylparathion hydrolase activity: 1663U/mL

Type  Sec/SPI



Structure Information


PDB ID  6C26,

Predicted Structure ID  SPKB00150.cif

Structure  SPKB00150.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2638.14274

Aliphatic index  97.27272727

Isoelectric point  8.549912035

Charge (pH=7)   0.936006272

Topological polar surface area  914.77

Aromaticity  0.272727273

Average rotatable bonds  3.636363636

Number of hydrogen bond donors  34

Number of hydrogen bond acceptors  31

X logP energy  -3.18053

Hydropathy 



Literature Information


Title  Preparation method of translational co-transfer signal peptide and recombinant parathion-methyl hydrolase

DOI  NA,

Publication Year  2018

PubMed ID  NA,

Patent ID  CN108676077A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.