SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00149

Signal sequence   MKLAYSLLLLLAGVSASVINYKRDGD

Length  26

Organism  Artificial

UniProt ID  NA,

Motif  1..26



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  Increase inulinase activity by 5.1 times

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00149.cif

Structure  SPKB00149.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2811.33234

Aliphatic index  138.8461538

Isoelectric point  9.121157886

Charge (pH=7)   0.99658306

Topological polar surface area  1123.6

Aromaticity  0.076923077

Average rotatable bonds  3.653846154

Number of hydrogen bond donors  40

Number of hydrogen bond acceptors  39

X logP energy  -8.55183

Hydropathy 



Literature Information


Title  Kluyveromyces marxianus promoter, secretory signal peptide, and preparation and application of kluyveromyces marxianus promoter and secretory signal peptide

DOI  NA,

Publication Year  2018

PubMed ID  NA,

Patent ID  CN108410870A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.