SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00144

Signal sequence   MKKKRKGCFAAAGFMMIFVFVIA

Length  23

Organism  Artificial

UniProt ID  NA,

Motif  1..23



Activity Information


Pathway  NA

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  Beta-Galactosidase: 5.76U/mL

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00144.cif

Structure  SPKB00144.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2595.32514

Aliphatic index  76.52173913

Isoelectric point  11.24912534

Charge (pH=7)   4.934826137

Topological polar surface area  869.5

Aromaticity  0.173913043

Average rotatable bonds  3.869565217

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  33

X logP energy  -2.25033

Hydropathy 



Literature Information


Title  Signal peptide capable of improving secretion efficiency and application of peptide

DOI  NA,

Publication Year  2018

PubMed ID  NA,

Patent ID  CN107857801A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.