SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00143

Signal sequence   MKKKKTWKRTHVENILRILLPPIMILSLILPTPPIEASA

Length  39

Organism  Artificial

UniProt ID  NA,

Motif  1..39



Activity Information


Pathway  NA

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  Increase keratinase activity by 3.39 times

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00143.cif

Structure  SPKB00143.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4491.59324

Aliphatic index  132.5641026

Isoelectric point  11.33634647

Charge (pH=7)   5.090961844

Topological polar surface area  1642.38

Aromaticity  0.025641026

Average rotatable bonds  3.794871795

Number of hydrogen bond donors  56

Number of hydrogen bond acceptors  58

X logP energy  -7.29976

Hydropathy 



Literature Information


Title  Signal peptide for optimizing high-level secretory expression of keratinase Ker and application of signal peptide

DOI  NA,

Publication Year  2017

PubMed ID  NA,

Patent ID  CN107200772A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.