SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00139

Signal sequence   KSCFACLVCFMGRKKRRQRRR

Length  21

Organism  Human immunodeficiency virus type 1

UniProt ID  NA,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00139.cif

Structure  SPKB00139.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2630.25634

Aliphatic index  37.14285714

Isoelectric point  12.23351329

Charge (pH=7)   8.811155182

Topological polar surface area  1158.1

Aromaticity  0.095238095

Average rotatable bonds  4.476190476

Number of hydrogen bond donors  48

Number of hydrogen bond acceptors  37

X logP energy  -12.29998

Hydropathy 



Literature Information


Title  Cell membrane localization signal peptide as well as encoding gene and application thereof

DOI  NA,

Publication Year  2017

PubMed ID  NA,

Patent ID  CN107056899A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.