SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00130

Signal sequence   MFLKSLLSFASILTLCKA

Length  18

Organism  Komagataella phaffii

UniProt ID  C4QZV5,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00130.cif

Structure  SPKB00130.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1986.50174

Aliphatic index  141.1111111

Isoelectric point  9.676237541

Charge (pH=7)   1.935419516

Topological polar surface area  690.98

Aromaticity  0.111111111

Average rotatable bonds  3.722222222

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  27

X logP energy  -3.2597

Hydropathy 



Literature Information


Title  Endogenous signal peptides of Pichia pastoris and application thereof

DOI  NA,

Publication Year  2017

PubMed ID  NA,

Patent ID  CN106319638A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.