SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00128

Signal sequence   MRNHLNDLVVLFLLLTVAAQA

Length  21

Organism  Komagataella phaffii

UniProt ID  C4R7S4,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00128.cif

Structure  SPKB00128.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2351.83564

Aliphatic index  167.1428571

Isoelectric point  7.550936504

Charge (pH=7)   0.089336563

Topological polar surface area  922.7

Aromaticity  0.047619048

Average rotatable bonds  3.666666667

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  30

X logP energy  -5.50473

Hydropathy 



Literature Information


Title  Endogenous signal peptides of Pichia pastoris and application thereof

DOI  NA,

Publication Year  2017

PubMed ID  NA,

Patent ID  CN106319638A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.