SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00127

Signal sequence   MINLNSFLILTVTLLSPALA

Length  20

Organism  Komagataella phaffii

UniProt ID  C4QVR8,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00127.cif

Structure  SPKB00127.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2144.64074

Aliphatic index  180.5

Isoelectric point  6.099999998

Charge (pH=7)   -0.002015701

Topological polar surface area  774.53

Aromaticity  0.05

Average rotatable bonds  3.4

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  28

X logP energy  -4.3269

Hydropathy 



Literature Information


Title  Endogenous signal peptides of Pichia pastoris and application thereof

DOI  NA,

Publication Year  2017

PubMed ID  NA,

Patent ID  CN106319638A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.