SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00124

Signal sequence   WEHDEL

Length  6

Organism  Artificial

UniProt ID  NA,

Motif  1..6



Activity Information


Pathway  Endoplasmic reticulum retention pathway

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00124.cif

Structure  SPKB00124.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  827.84854

Aliphatic index  65

Isoelectric point  3.926331413

Charge (pH=7)   -2.90710988

Topological polar surface area  365.19

Aromaticity  0.166666667

Average rotatable bonds  4.166666667

Number of hydrogen bond donors  12

Number of hydrogen bond acceptors  11

X logP energy  -1.2375

Hydropathy 



Literature Information


Title  Retention effect-enhanced endoplasmic reticulum retention signal peptide mutant

DOI  NA,

Publication Year  2016

PubMed ID  NA,

Patent ID  CN105294837A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.