SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00121

Signal sequence   MGKWVKVLFALICIAVAYS

Length  19

Organism  Artificial

UniProt ID  NA,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  Bevacizumab: 4.2ug/mL

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00121.cif

Structure  SPKB00121.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2112.66254

Aliphatic index  143.6842105

Isoelectric point  9.405774727

Charge (pH=7)   1.934569102

Topological polar surface area  695.41

Aromaticity  0.157894737

Average rotatable bonds  3.526315789

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  26

X logP energy  -0.1836

Hydropathy 



Literature Information


Title  Signal peptide for protein expression

DOI  NA,

Publication Year  2015

PubMed ID  NA,

Patent ID  CN104974226A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.