Peptide-Information

General Information

SPKB ID SPKB00120

Signal sequence MKYLLPTAAAGLLLLAAQPAMA

Length 22

Organism Homo sapiens (Human)

UniProt ID NA,

Motif 1..22

Activity Information

Pathway SRP-dependent

Natural/Artificial Artificial

Subcellular location ER

Secretion efficiency NA

Type Sec/SPI

Structure Information

PDB ID 1QOK,

Predicted Structure ID SPKB00120.cif

Structure SPKB00120.cif

Very high (pLDDT > 90)

Confident (90 > pLDDT > 70)

Low (70 > pLDDT > 50)

Very low (pLDDT < 50)

Loading PAE…

Expected Position Error (Ångströms)

Physicochemical Information

Molecular weight 2228.77964

Aliphatic index 138.1818182

Isoelectric point 9.298300651

Charge (pH=7) 0.996838851

Topological polar surface area 766.41

Aromaticity 0.045454545

Average rotatable bonds 3.136363636

Number of hydrogen bond donors 25

Number of hydrogen bond acceptors 29

X logP energy -3.1314

Hydropathy

Literature Information

Title Optimised heavy chain and light chain signal peptides for the production of recombinant antibody therapeutics

DOI NA,

Publication Year 2015

PubMed ID NA,