Peptide-Information

General Information

SPKB ID SPKB00119

Signal sequence MDLLHKNMKHLWFFLLLVAAPRWVLS

Length 26

Organism Homo sapiens (Human)

UniProt ID NA,

Motif 1..26

Activity Information

Pathway SRP-dependent

Natural/Artificial Artificial

Subcellular location ER

Secretion efficiency NA

Type Sec/SPI

Structure Information

PDB ID 7MX8,

Predicted Structure ID SPKB00119.cif

Structure SPKB00119.cif

Very high (pLDDT > 90)

Confident (90 > pLDDT > 70)

Low (70 > pLDDT > 50)

Very low (pLDDT < 50)

Loading PAE…

Expected Position Error (Ångströms)

Physicochemical Information

Molecular weight 3179.92384

Aliphatic index 135

Isoelectric point 10.78909426

Charge (pH=7) 2.179655586

Topological polar surface area 1085.53

Aromaticity 0.153846154

Average rotatable bonds 3.884615385

Number of hydrogen bond donors 38

Number of hydrogen bond acceptors 37

X logP energy -0.06613

Hydropathy

Literature Information

Title Optimised heavy chain and light chain signal peptides for the production of recombinant antibody therapeutics

DOI NA,

Publication Year 2015

PubMed ID NA,