Peptide-Information

General Information

SPKB ID SPKB00118

Signal sequence MEFGLSWVFLVALFRGVQC

Length 19

Organism Homo sapiens (Human)

UniProt ID NA,

Motif 1..19

Activity Information

Pathway SRP-dependent

Natural/Artificial Artificial

Subcellular location ER

Secretion efficiency NA

Type Sec/SPI

Structure Information

PDB ID NA,

Predicted Structure ID SPKB00118.cif

Structure SPKB00118.cif

Very high (pLDDT > 90)

Confident (90 > pLDDT > 70)

Low (70 > pLDDT > 50)

Very low (pLDDT < 50)

Loading PAE…

Expected Position Error (Ångströms)

Physicochemical Information

Molecular weight 2202.66014

Aliphatic index 112.6315789

Isoelectric point 6.232433001

Charge (pH=7) -0.062218605

Topological polar surface area 765.43

Aromaticity 0.210526316

Average rotatable bonds 3.631578947

Number of hydrogen bond donors 28

Number of hydrogen bond acceptors 26

X logP energy -1.96543

Hydropathy

Literature Information

Title Optimised heavy chain and light chain signal peptides for the production of recombinant antibody therapeutics

DOI NA,

Publication Year 2015

PubMed ID NA,