Peptide-Information

General Information

SPKB ID SPKB00117

Signal sequence MELGLRWVFLVAILEGVQC

Length 19

Organism Homo sapiens (Human)

UniProt ID NA,

Motif 1..19

Activity Information

Pathway SRP-dependent

Natural/Artificial Artificial

Subcellular location ER

Secretion efficiency NA

Type Sec/SPI

Structure Information

PDB ID 5U68,

Predicted Structure ID SPKB00117.cif

Structure SPKB00117.cif

Very high (pLDDT > 90)

Confident (90 > pLDDT > 70)

Low (70 > pLDDT > 50)

Very low (pLDDT < 50)

Loading PAE…

Expected Position Error (Ångströms)

Physicochemical Information

Molecular weight 2176.66304

Aliphatic index 153.6842105

Isoelectric point 4.25810809

Charge (pH=7) -1.060443482

Topological polar surface area 782.5

Aromaticity 0.105263158

Average rotatable bonds 3.736842105

Number of hydrogen bond donors 28

Number of hydrogen bond acceptors 26

X logP energy -1.48613

Hydropathy

Literature Information

Title Optimised heavy chain and light chain signal peptides for the production of recombinant antibody therapeutics

DOI NA,

Publication Year 2015

PubMed ID NA,