SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00116

Signal sequence   MTKPTQVLVRSVSILFFITLLHLVVA

Length  26

Organism  Artificial

UniProt ID  NA,

Motif  1..26



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00116.cif

Structure  SPKB00116.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2926.64044

Aliphatic index  164.6153846

Isoelectric point  11.65178972

Charge (pH=7)   2.088595045

Topological polar surface area  1042.87

Aromaticity  0.076923077

Average rotatable bonds  3.615384615

Number of hydrogen bond donors  37

Number of hydrogen bond acceptors  37

X logP energy  -4.36383

Hydropathy 



Literature Information


Title  Method for optimizing signal peptide and improving exocytosis expression of trypsin

DOI  NA,

Publication Year  2015

PubMed ID  NA,

Patent ID  CN104312933A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.