SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00115

Signal sequence   MKLAYSLLLPLAGVSA

Length  16

Organism  Artificial

UniProt ID  NA,

Motif  1..16



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00115.cif

Structure  SPKB00115.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1647.04894

Aliphatic index  158.75

Isoelectric point  9.298300651

Charge (pH=7)   0.996838851

Topological polar surface area  577.74

Aromaticity  0.0625

Average rotatable bonds  3.25

Number of hydrogen bond donors  20

Number of hydrogen bond acceptors  22

X logP energy  -2.4309

Hydropathy 



Literature Information


Title  Method for optimizing signal peptide and improving exocytosis expression of trypsin

DOI  NA,

Publication Year  2015

PubMed ID  NA,

Patent ID  CN104312933A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.