SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00114

Signal sequence   MKWVTFISLLFLFSSAYS

Length  18

Organism  Artificial

UniProt ID  NA,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  4BKE,

Predicted Structure ID  SPKB00114.cif

Structure  SPKB00114.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2140.56784

Aliphatic index  108.3333333

Isoelectric point  9.298300651

Charge (pH=7)   0.996838851

Topological polar surface area  721.21

Aromaticity  0.277777778

Average rotatable bonds  3.666666667

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  27

X logP energy  -1.8673

Hydropathy 



Literature Information


Title  Method for optimizing signal peptide and improving exocytosis expression of trypsin

DOI  NA,

Publication Year  2015

PubMed ID  NA,

Patent ID  CN104312933A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.