SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00113

Signal sequence   MVAWWSLFLYGLQVAAPALA

Length  20

Organism  Artificial

UniProt ID  NA,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  6XSJ,

Predicted Structure ID  SPKB00113.cif

Structure  SPKB00113.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2207.66114

Aliphatic index  132

Isoelectric point  6.093198033

Charge (pH=7)   -0.002866115

Topological polar surface area  722.56

Aromaticity  0.2

Average rotatable bonds  3.15

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  25

X logP energy  -0.0071

Hydropathy 



Literature Information


Title  Method for optimizing signal peptide and improving exocytosis expression of trypsin

DOI  NA,

Publication Year  2015

PubMed ID  NA,

Patent ID  CN104312933A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.