SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00112

Signal sequence   MKLSLVAAMLLLLALVALLLLRSAARA

Length  27

Organism  Artificial

UniProt ID  NA,

Motif  1..27



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00112.cif

Structure  SPKB00112.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2835.67614

Aliphatic index  206.2962963

Isoelectric point  12.51647815

Charge (pH=7)   2.997682643

Topological polar surface area  1010.2

Aromaticity  0

Average rotatable bonds  3.592592593

Number of hydrogen bond donors  37

Number of hydrogen bond acceptors  35

X logP energy  -2.89216

Hydropathy 



Literature Information


Title  Novel signal sequences to improve protein expressions and secretion of recombinant enzymes and other proteins

DOI  NA,

Publication Year  2013

PubMed ID  NA,

Patent ID  CN103328649A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.