SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00110

Signal sequence   MKLSLVAAMLLLLWVALLLLSAARA

Length  25

Organism  Artificial

UniProt ID  NA,

Motif  1..25



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00110.cif

Structure  SPKB00110.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2681.46364

Aliphatic index  203.2

Isoelectric point  11.65177567

Charge (pH=7)   1.997685954

Topological polar surface area  905.89

Aromaticity  0.04

Average rotatable bonds  3.56

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  32

X logP energy  -0.46703

Hydropathy 



Literature Information


Title  Novel signal sequences to improve protein expressions and secretion of recombinant enzymes and other proteins

DOI  NA,

Publication Year  2013

PubMed ID  NA,

Patent ID  CN103328649A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.