SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00109

Signal sequence   MKLSLVAAMLLLLSLVAAMLLLLSAARA

Length  28

Organism  Artificial

UniProt ID  NA,

Motif  1..28



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00109.cif

Structure  SPKB00109.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2897.75944

Aliphatic index  198.9285714

Isoelectric point  11.65177567

Charge (pH=7)   1.997685954

Topological polar surface area  997.63

Aromaticity  0

Average rotatable bonds  3.535714286

Number of hydrogen bond donors  36

Number of hydrogen bond acceptors  37

X logP energy  -2.92523

Hydropathy 



Literature Information


Title  Novel signal sequences to improve protein expressions and secretion of recombinant enzymes and other proteins

DOI  NA,

Publication Year  2013

PubMed ID  NA,

Patent ID  CN103328649A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.