SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00095

Signal sequence   MKKMNLAVCIATLMGTAGLMGTAVA

Length  25

Organism  Artificial

UniProt ID  NA,

Motif  1..25



Activity Information


Pathway  Sec

Natural/Artificial  Artificial

Subcellular location  periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00095.cif

Structure  SPKB00095.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2497.14424

Aliphatic index  105.6

Isoelectric point  9.676237541

Charge (pH=7)   1.935419516

Topological polar surface area  917.54

Aromaticity  0

Average rotatable bonds  3.4

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  37

X logP energy  -8.2584

Hydropathy 



Literature Information


Title  Signal sequence for production of leu-hirudine via secretion by E coli in culture medium

DOI  NA,

Publication Year  2005

PubMed ID  NA,

Patent ID  CN1192037C,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.