SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00089

Signal sequence   MKKTIAFLLASLFVFSIATVAQA

Length  23

Organism  Escherichia coli

UniProt ID  NA,

Motif  1..23



Activity Information


Pathway  NA

Natural/Artificial  Artificial

Subcellular location  periplasmic space

Secretion efficiency  NA

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00089.cif

Structure  SPKB00089.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2471.03934

Aliphatic index  131.7391304

Isoelectric point  10.80537956

Charge (pH=7)   1.997394232

Topological polar surface area  879.57

Aromaticity  0.130434783

Average rotatable bonds  3.52173913

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  32

X logP energy  -4.5432

Hydropathy 



Literature Information


Title  Modified i CE.(oli) enterotoxin II signal peptide and microorganism expressing fusion protein of said peptide and heterologous protein

DOI  NA,

Publication Year  2004

PubMed ID  NA,

Patent ID  CN1144815C,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.