SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00082

Signal sequence   MKKNIAFLLASMFVFSIATNAYA

Length  23

Organism  Escherichia coli

UniProt ID  P22542,

Motif  1..23



Activity Information


Pathway  NA

Natural/Artificial  Natural

Subcellular location  periplasmic space

Secretion efficiency  NA

Type  NA



Structure Information


PDB ID  3SOB,

Predicted Structure ID  SPKB00082.cif

Structure  SPKB00082.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2552.08774

Aliphatic index  102.173913

Isoelectric point  10.24760792

Charge (pH=7)   1.996543817

Topological polar surface area  922.66

Aromaticity  0.173913043

Average rotatable bonds  3.608695652

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  34

X logP energy  -5.4394

Hydropathy 



Literature Information


Title  Modified i CE.(oli) enterotoxin II signal peptide and microorganism expressing fusion protein of said peptide and heterologous protein

DOI  NA,

Publication Year  2004

PubMed ID  NA,

Patent ID  CN1144815C,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.