SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00076

Signal sequence   MMRPIVLVLLFATSALA

Length  17

Organism  Artificial

UniProt ID  NA,

Motif  1..17



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00076.cif

Structure  SPKB00076.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1846.36314

Aliphatic index  166.4705882

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  622.49

Aromaticity  0.058823529

Average rotatable bonds  3.411764706

Number of hydrogen bond donors  22

Number of hydrogen bond acceptors  23

X logP energy  -1.35123

Hydropathy 



Literature Information


Title  Mammalian expression vector with a highly efficient secretory signal sequence

DOI  NA,

Publication Year  2010

PubMed ID  NA,

Patent ID  CN101687910A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.