SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00075

Signal sequence   MKTLILAVALVYCATVHC

Length  18

Organism  Artificial

UniProt ID  NA,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00075.cif

Structure  SPKB00075.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1949.45864

Aliphatic index  151.6666667

Isoelectric point  8.232794593

Charge (pH=7)   0.96379851

Topological polar surface area  673.41

Aromaticity  0.055555556

Average rotatable bonds  3.388888889

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  27

X logP energy  -2.7306

Hydropathy 



Literature Information


Title  Mammalian expression vector with a highly efficient secretory signal sequence

DOI  NA,

Publication Year  2010

PubMed ID  NA,

Patent ID  CN101687910A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.