SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00074

Signal sequence   MRTLWIMAVLLLGVEG

Length  16

Organism  Artificial

UniProt ID  NA,

Motif  1..16



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00074.cif

Structure  SPKB00074.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1802.26654

Aliphatic index  164.375

Isoelectric point  6.410149741

Charge (pH=7)   -0.000243889

Topological polar surface area  635.04

Aromaticity  0.0625

Average rotatable bonds  3.6875

Number of hydrogen bond donors  23

Number of hydrogen bond acceptors  22

X logP energy  -0.76543

Hydropathy 



Literature Information


Title  Mammalian expression vector with a highly efficient secretory signal sequence

DOI  NA,

Publication Year  2010

PubMed ID  NA,

Patent ID  CN101687910A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.