SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00072

Signal sequence   MRFFFVFLAIVLFQGIHG

Length  18

Organism  Artificial

UniProt ID  NA,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00072.cif

Structure  SPKB00072.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2142.63554

Aliphatic index  124.4444444

Isoelectric point  10.5517587

Charge (pH=7)   1.088890079

Topological polar surface area  691.69

Aromaticity  0.277777778

Average rotatable bonds  3.722222222

Number of hydrogen bond donors  24

Number of hydrogen bond acceptors  23

X logP energy  0.88017

Hydropathy 



Literature Information


Title  Mammalian expression vector with a highly efficient secretory signal sequence

DOI  NA,

Publication Year  2010

PubMed ID  NA,

Patent ID  CN101687910A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.