SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00071

Signal sequence   MKKRKRRNFKRFIAAFLVLALMISLVPADVLAKST

Length  35

Organism  Bacillus subtilis

UniProt ID  NA,

Motif  1..35



Activity Information


Pathway  NA

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  Increase asparaginase production by 1.5 times

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00071.cif

Structure  SPKB00071.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4034.02894

Aliphatic index  117.1428571

Isoelectric point  12.53897435

Charge (pH=7)   7.996942369

Topological polar surface area  1562.71

Aromaticity  0.085714286

Average rotatable bonds  4

Number of hydrogen bond donors  57

Number of hydrogen bond acceptors  52

X logP energy  -9.57422

Hydropathy 



Literature Information


Title  Signal peptide capable of improving secretion efficiency, and applications thereof

DOI  NA,

Publication Year  2014

PubMed ID  NA,

Patent ID  CN103709236A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.