SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00070

Signal sequence   MKKVILAAFILVGSTLGAFSFSSDASA

Length  27

Organism  Bacillus subtilis

UniProt ID  NA,

Motif  1..27



Activity Information


Pathway  NA

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  Increase Savinase production by 3.7 times

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00070.cif

Structure  SPKB00070.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2732.23054

Aliphatic index  112.2222222

Isoelectric point  9.537297863

Charge (pH=7)   0.997840716

Topological polar surface area  1030.64

Aromaticity  0.111111111

Average rotatable bonds  3.333333333

Number of hydrogen bond donors  37

Number of hydrogen bond acceptors  38

X logP energy  -9.5359

Hydropathy 



Literature Information


Title  Signal peptide optimizing efficient secretory expression of Savinase and application thereof

DOI  NA,

Publication Year  2014

PubMed ID  NA,

Patent ID  CN103483432A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.