SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00037

Signal sequence   MERCLATLVERLCVAVVERACALAMKKTAIAIAVALAGFATVAQA

Length  45

Organism  Escherichia coli

UniProt ID  NA,

Motif  1..45



Activity Information


Pathway  Sec

Natural/Artificial  Artificial

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00037.cif

Structure  SPKB00037.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4648.68434

Aliphatic index  128.2222222

Isoelectric point  8.520327277

Charge (pH=7)   1.816785518

Topological polar surface area  1797.14

Aromaticity  0.022222222

Average rotatable bonds  3.444444444

Number of hydrogen bond donors  67

Number of hydrogen bond acceptors  63

X logP energy  -14.53329

Hydropathy 



Literature Information


Title  Small peptide strengthening mold sequence of strong secretory signal peptide and application thereof

DOI  NA,

Publication Year  2013

PubMed ID  NA,

Patent ID  CN103254277A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.