SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00035

Signal sequence   MERACALAVERACALMKKTAIAIAVALAGFATVAQA

Length  36

Organism  Escherichia coli

UniProt ID  NA,

Motif  1..36



Activity Information


Pathway  Sec

Natural/Artificial  Artificial

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00035.cif

Structure  SPKB00035.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3635.42084

Aliphatic index  114.4444444

Isoelectric point  8.821438466

Charge (pH=7)   1.876988423

Topological polar surface area  1415.81

Aromaticity  0.027777778

Average rotatable bonds  3.361111111

Number of hydrogen bond donors  52

Number of hydrogen bond acceptors  50

X logP energy  -12.39536

Hydropathy 



Literature Information


Title  Small peptide strengthening mold sequence of strong secretory signal peptide and application thereof

DOI  NA,

Publication Year  2013

PubMed ID  NA,

Patent ID  CN103254277A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.