SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00034

Signal sequence   MERACVAVMERACVAVMKKTAIAIAVALAGFATVAQA

Length  37

Organism  Escherichia coli

UniProt ID  NA,

Motif  1..37



Activity Information


Pathway  Sec

Natural/Artificial  Artificial

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00034.cif

Structure  SPKB00034.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3766.61364

Aliphatic index  111.0810811

Isoelectric point  8.821438466

Charge (pH=7)   1.876988423

Topological polar surface area  1444.91

Aromaticity  0.027027027

Average rotatable bonds  3.378378378

Number of hydrogen bond donors  53

Number of hydrogen bond acceptors  52

X logP energy  -12.30156

Hydropathy 



Literature Information


Title  Small peptide strengthening mold sequence of strong secretory signal peptide and application thereof

DOI  NA,

Publication Year  2013

PubMed ID  NA,

Patent ID  CN103254277A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.