SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00033

Signal sequence   MERTTLTCCCCCCMKKTAIAIAVALAGFATVAQA

Length  34

Organism  Escherichia coli

UniProt ID  NA,

Motif  1..34



Activity Information


Pathway  Sec

Natural/Artificial  Artificial

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  1PKQ,

Predicted Structure ID  SPKB00033.cif

Structure  SPKB00033.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3498.30234

Aliphatic index  86.47058824

Isoelectric point  8.11449821

Charge (pH=7)   1.627317748

Topological polar surface area  1319.1

Aromaticity  0.029411765

Average rotatable bonds  3.352941176

Number of hydrogen bond donors  53

Number of hydrogen bond acceptors  53

X logP energy  -14.43303

Hydropathy 



Literature Information


Title  Small peptide strengthening mold sequence of strong secretory signal peptide and application thereof

DOI  NA,

Publication Year  2013

PubMed ID  NA,

Patent ID  CN103254277A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.