SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00032

Signal sequence   MLTKCLECATACCCCCCMKKTAIAIAVALAGFATVAQA

Length  38

Organism  Escherichia coli

UniProt ID  NA,

Motif  1..38



Activity Information


Pathway  Sec

Natural/Artificial  Artificial

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  1PKQ,

Predicted Structure ID  SPKB00032.cif

Structure  SPKB00032.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3830.77844

Aliphatic index  92.89473684

Isoelectric point  7.965235326

Charge (pH=7)   1.503076593

Topological polar surface area  1379.39

Aromaticity  0.026315789

Average rotatable bonds  3.289473684

Number of hydrogen bond donors  56

Number of hydrogen bond acceptors  58

X logP energy  -14.0634

Hydropathy 



Literature Information


Title  Small peptide strengthening mold sequence of strong secretory signal peptide and application thereof

DOI  NA,

Publication Year  2013

PubMed ID  NA,

Patent ID  CN103254277A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.