SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00023

Signal sequence   MDKACVAVMKKTAIAIAVALAGFATVAQA

Length  29

Organism  Escherichia coli

UniProt ID  NA,

Motif  1..29



Activity Information


Pathway  Sec

Natural/Artificial  Artificial

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00023.cif

Structure  SPKB00023.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2864.51614

Aliphatic index  114.8275862

Isoelectric point  9.581484403

Charge (pH=7)   1.935570966

Topological polar surface area  1077.03

Aromaticity  0.034482759

Average rotatable bonds  3.275862069

Number of hydrogen bond donors  38

Number of hydrogen bond acceptors  40

X logP energy  -8.8671

Hydropathy 



Literature Information


Title  Small peptide strengthening mold sequence of strong secretory signal peptide and application thereof

DOI  NA,

Publication Year  2013

PubMed ID  NA,

Patent ID  CN103254277A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.