SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00022

Signal sequence   MEARACVAVMKKTAIAIAVALAGFATVAQA

Length  30

Organism  Escherichia coli

UniProt ID  NA,

Motif  1..30



Activity Information


Pathway  Sec

Natural/Artificial  Artificial

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00022.cif

Structure  SPKB00022.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2977.63524

Aliphatic index  114.3333333

Isoelectric point  9.673754512

Charge (pH=7)   1.937191327

Topological polar surface area  1142.01

Aromaticity  0.033333333

Average rotatable bonds  3.266666667

Number of hydrogen bond donors  41

Number of hydrogen bond acceptors  41

X logP energy  -9.83803

Hydropathy 



Literature Information


Title  Small peptide strengthening mold sequence of strong secretory signal peptide and application thereof

DOI  NA,

Publication Year  2013

PubMed ID  NA,

Patent ID  CN103254277A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.