SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00019

Signal sequence   MCLERACALAMKKTAIAIAVALAGFATVAQA

Length  31

Organism  Escherichia coli

UniProt ID  NA,

Motif  1..31



Activity Information


Pathway  Sec

Natural/Artificial  Artificial

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  1PKQ,

Predicted Structure ID  SPKB00019.cif

Structure  SPKB00019.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3108.82764

Aliphatic index  117.0967742

Isoelectric point  8.821557977

Charge (pH=7)   1.875216611

Topological polar surface area  1171.11

Aromaticity  0.032258065

Average rotatable bonds  3.322580645

Number of hydrogen bond donors  43

Number of hydrogen bond acceptors  43

X logP energy  -9.64323

Hydropathy 



Literature Information


Title  Small peptide strengthening mold sequence of strong secretory signal peptide and application thereof

DOI  NA,

Publication Year  2013

PubMed ID  NA,

Patent ID  CN103254277A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.