SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00018

Signal sequence   MERACALAMKKTAIAIAVALAGFATVAQA

Length  29

Organism  Escherichia coli

UniProt ID  NA,

Motif  1..29



Activity Information


Pathway  Sec

Natural/Artificial  Artificial

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  1PKQ,

Predicted Structure ID  SPKB00018.cif

Structure  SPKB00018.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2892.52944

Aliphatic index  111.7241379

Isoelectric point  9.673754512

Charge (pH=7)   1.937191327

Topological polar surface area  1112.91

Aromaticity  0.034482759

Average rotatable bonds  3.310344828

Number of hydrogen bond donors  40

Number of hydrogen bond acceptors  40

X logP energy  -9.58873

Hydropathy 



Literature Information


Title  Small peptide strengthening mold sequence of strong secretory signal peptide and application thereof

DOI  NA,

Publication Year  2013

PubMed ID  NA,

Patent ID  CN103254277A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.