SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00016

Signal sequence   MERACALMKKTAIAIAVALAGFATVAQA

Length  28

Organism  Escherichia coli

UniProt ID  NA,

Motif  1..28



Activity Information


Pathway  Sec

Natural/Artificial  Artificial

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  1PKQ,

Predicted Structure ID  SPKB00016.cif

Structure  SPKB00016.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2821.45064

Aliphatic index  112.1428571

Isoelectric point  9.673754512

Charge (pH=7)   1.937191327

Topological polar surface area  1083.81

Aromaticity  0.035714286

Average rotatable bonds  3.357142857

Number of hydrogen bond donors  39

Number of hydrogen bond acceptors  39

X logP energy  -9.09343

Hydropathy 



Literature Information


Title  Small peptide strengthening mold sequence of strong secretory signal peptide and application thereof

DOI  NA,

Publication Year  2013

PubMed ID  NA,

Patent ID  CN103254277A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.