SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00013

Signal sequence   MERLCMKKTAIAIAVALAGFATVAQA

Length  26

Organism  Escherichia coli

UniProt ID  NA,

Motif  1..26



Activity Information


Pathway  Sec

Natural/Artificial  Artificial

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  1PKQ,

Predicted Structure ID  SPKB00013.cif

Structure  SPKB00013.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2679.29304

Aliphatic index  113.0769231

Isoelectric point  9.673754512

Charge (pH=7)   1.937191327

Topological polar surface area  1025.61

Aromaticity  0.038461538

Average rotatable bonds  3.461538462

Number of hydrogen bond donors  37

Number of hydrogen bond acceptors  37

X logP energy  -8.10283

Hydropathy 



Literature Information


Title  Small peptide strengthening mold sequence of strong secretory signal peptide and application thereof

DOI  NA,

Publication Year  2013

PubMed ID  NA,

Patent ID  CN103254277A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.