SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00012

Signal sequence   MREIVMKKTAIAIAVALAGFATVAQA

Length  26

Organism  Escherichia coli

UniProt ID  NA,

Motif  1..26



Activity Information


Pathway  Sec

Natural/Artificial  Artificial

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  1PKQ,

Predicted Structure ID  SPKB00012.cif

Structure  SPKB00012.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2675.28684

Aliphatic index  124.2307692

Isoelectric point  10.7890093

Charge (pH=7)   1.999166043

Topological polar surface area  1025.61

Aromaticity  0.038461538

Average rotatable bonds  3.461538462

Number of hydrogen bond donors  36

Number of hydrogen bond acceptors  36

X logP energy  -7.37663

Hydropathy 



Literature Information


Title  Small peptide strengthening mold sequence of strong secretory signal peptide and application thereof

DOI  NA,

Publication Year  2013

PubMed ID  NA,

Patent ID  CN103254277A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.