SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00009

Signal sequence   MERAMKKTAIAIAVALAGFATVAQA

Length  25

Organism  Escherichia coli

UniProt ID  NA,

Motif  1..25



Activity Information


Pathway  Sec

Natural/Artificial  Artificial

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  1PKQ,

Predicted Structure ID  SPKB00009.cif

Structure  SPKB00009.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2534.07364

Aliphatic index  106

Isoelectric point  10.7890093

Charge (pH=7)   1.999166043

Topological polar surface area  996.51

Aromaticity  0.04

Average rotatable bonds  3.4

Number of hydrogen bond donors  35

Number of hydrogen bond acceptors  35

X logP energy  -8.54363

Hydropathy 



Literature Information


Title  Small peptide strengthening mold sequence of strong secretory signal peptide and application thereof

DOI  NA,

Publication Year  2013

PubMed ID  NA,

Patent ID  CN103254277A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.