SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00005

Signal sequence   MDVPLQLLGLLLLWLSGVRC

Length  20

Organism  Artificial

UniProt ID  NA,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  Erythropoietin: 85ng/ml

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00005.cif

Structure  SPKB00005.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2239.80574

Aliphatic index  185

Isoelectric point  6.161167719

Charge (pH=7)   -0.063547244

Topological polar surface area  785.74

Aromaticity  0.05

Average rotatable bonds  3.6

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  27

X logP energy  -1.53803

Hydropathy 



Literature Information


Title  Artificially synthesized signal peptide and application thereof

DOI  NA,

Publication Year  2010

PubMed ID  NA,

Patent ID  CN101921315A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.