SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00004

Signal sequence   MRVLPEFLGLLLLWISGVRC

Length  20

Organism  Artificial

UniProt ID  NA,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  Erythropoietin: 62ng/ml

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00004.cif

Structure  SPKB00004.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2315.90664

Aliphatic index  165.5

Isoelectric point  8.549845238

Charge (pH=7)   0.937778084

Topological polar surface area  804.55

Aromaticity  0.1

Average rotatable bonds  3.7

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  27

X logP energy  -0.95356

Hydropathy 



Literature Information


Title  Artificially synthesized signal peptide and application thereof

DOI  NA,

Publication Year  2010

PubMed ID  NA,

Patent ID  CN101921315A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.