SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00003

Signal sequence   MDVPAEFLGLLLLWLSGVRC

Length  20

Organism  Artificial

UniProt ID  NA,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  Erythropoietin: 100ng/ml

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00003.cif

Structure  SPKB00003.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2232.72714

Aliphatic index  151

Isoelectric point  4.184374695

Charge (pH=7)   -1.061772121

Topological polar surface area  779.95

Aromaticity  0.1

Average rotatable bonds  3.5

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  27

X logP energy  -1.76833

Hydropathy 



Literature Information


Title  Artificially synthesized signal peptide and application thereof

DOI  NA,

Publication Year  2010

PubMed ID  NA,

Patent ID  CN101921315A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.