SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00002

Signal sequence   MDVLAFLLGLLLLWLPGVRC

Length  20

Organism  Artificial

UniProt ID  NA,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  Erythropoietin: 73ng/ml

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00002.cif

Structure  SPKB00002.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2242.85224

Aliphatic index  190

Isoelectric point  6.161167719

Charge (pH=7)   -0.063547244

Topological polar surface area  722.42

Aromaticity  0.1

Average rotatable bonds  3.5

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  25

X logP energy  1.46677

Hydropathy 



Literature Information


Title  Artificially synthesized signal peptide and application thereof

DOI  NA,

Publication Year  2010

PubMed ID  NA,

Patent ID  CN101921315A,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.